Summary of key studies

Tab. Summary of key studies on the lung microbiota in chronic, acute, and other types of lung diseases.
# Disease Study Project code PMID Specimen Design and sample size Methods Key findings

Drug resistance analysis

Introduction
To gain a comprehensive understanding of drug resistance and virulence factors (VF) in the context of respiratory diseases, we performed analysis of antibiotic resistance (AR) and virulence factors in HLMA by using ShortBRED , with the Comprehensive Antibiotic Resistance Database (CARD) and Virulence Factors Database (VFDB).
Workflow
  • Step 1: Please select a dataset or directly search a dataset
    e.g. PRJEB7248
  • Step 2: Please select a drug resistance analysis
Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer.
Nr. of samples:
98
Body sites:
Lung
Country region:
USA
Instrument model:
NextSeq 500
Sequencing strategy:
mNGs
Center name:
Children's National Medical Center
Healthy status:
CF
Tab. 1 Summary of antibiotic resistance (AR) in PRJEB7248 .
# runCode Antimicrobial resistance profile Confers resistance to Phenotype ARO Number of detected AR genes Number of markers Number of reads Phenotype description
Tab. 2 Summary of the abundance of antibiotic resistance(AR) observed in PRJEB7248 .
# runCode Peptide Marker Classification Confers Resistance To Confers-Resistance-To ARO Phenotype ARO Gene ARO Gene Annotation Depth Combined Abundance Abundance Normalized Abundance

Differential abundance test

The tool enables users to submit their new data for detection of differential abundance taxa. Please fill in the form and upload the transcriptomic data with its sample information to process the submission.
Notes: The "*" symbol indicates the required fields.
Basic info
Parameters setting
Uploading
database Taxa info
Example file download
upload
Relative abundance matrix/counts matrix
Drop files here or click to upload (Less than 1GB).
database Group info
Example file download
upload
Meta-data of sample(s)
Drop files here or click to upload (Less than 1GB).